杨亮茹，女，博士，教授，博士研究生导师，河南省教育厅学术技术带头人，郑州市科技创新骨干，河南工业大学科技工作先进个人、优秀硕士学位论文指导教师、本科生毕业论文优秀指导教师、校长教学质量奖获得者。

联系方式：

电话：18623717909；E-mail：lryang@haut.edu.cn

教育经历：

(1) 1994.09至1998.06，郑州大学，化学，本科

(2) 1998.09至2003.06，郑州大学，有机化学，博士

博士后工作经历：

(1) 2003.09至2004.09，奥地利因斯布鲁克大学(Universität Innsbruck, Austria)

(2) 2004.10至2007.10，瑞士弗里堡大学(University of Fribourg, Switzerland)

科研与学术工作经历：

(1) 2008.03至2010.10，河南工业大学，化学化工学院，讲师

(2) 2010.10至2016.12，河南工业大学，化学化工学院，副教授

(3) 2017.01 至今，河南工业大学，化学化工学院，教授

(4) 2017.11至2018.11，美国德克萨斯大学西南医学中心(UT Southwestern Medical Center, USA)，放射系，访问学者

主要研究方向：金属有机化学，有机合成及催化，药物合成

主持的科研项目：

1. 国家自然科学基金面上项目，21172055，螯合型和钳形六元氮杂环卡宾钯化合物及其对碳-碳成键的催化，2012.01-2015.12，60万元，结题

2. 国家自然科学基金青年项目，20902017，非经典型卡宾金属化合物的合成、性质及应用研究，2010.01-2010.12，12万元，结题

3. 河南省自然科学基金重点项目，252300421284，手性钳形氮杂环卡宾金属化合物的合成及其在光催化反应中的应用，2025.01-2027.12，30万元，在研

4. 河南省自然科学基金面上项目，242300420186，手性钳形氮杂环卡宾过渡金属化合物的合成及其光催化性能研究，2024.01-2025.12，在研

5. 河南省科技发展计划，212102310332，靶向抗癌药物尼拉帕尼的合成研究，2021.01-2022.12，10万元，结题

6. 2020年度河南省留学人员科研择优资助项目，具有前列腺癌靶向诊断和个性治疗作用荧光探针的设计合成及性能研究，2020.01-2021.12，3万元，结题

7. 教育部留学回国人员科研启动基金，非经典型卡宾金属化合物的合成、性质及应用研究，2010.01-2011.12，4万元，结题

8. 河南省教育厅科学技术研究重点项目基础研究计划，18A150004，手性钳形氮杂环卡宾镍化合物的合成及不对称催化应用，2018.01-2019.12，5万元，结题

9. 河南工业大学国家自然基金培育项目支持计划，手性钳形氮杂环卡宾过渡金属化合物的合成及其光催化性能研究，2024.07-2026.06，6.5万元，在研

10. 河南工业大学科技创新人才培育计划项目，2017RCJH08，基于天然手法源氮杂环卡宾钯化合物的催化性能研究，2017.06-2020.12，8万元，结题

11. 河南工业大学科技创新人才培育计划项目，11CXRC10，基于天然氨基酸的手性氮杂环卡宾镍化合物及其催化氢化性能，2012.01-2016.12，8万元，结题

发表的部分学术论文：

1. Liangru Yang, Yaowen Liu, Xiaoqiong Diao, Xianggui Zeng, Yongmei Xiao, Jinwei Yuan, Pu Mao. New chelating N-heterocyclic carbene palladium complexes immobilized on magneticnanoparticles: Synthesis, characterization and catalytic properties. Appl. Organomet. Chem. 2024, 38(9), e7636.

2. Hongzhao Qu, Jinwei Yuan, Zhendong Feng, Na Guo, Yanli Yin, Liangru Yang, Yongmei Xiao, Lingbo Qu. Visible-light-promoted difluoromethylation/ cyclization of 1-acryloyl-2-cyanoindole for construction of difluoromethylated pyrrolo[1,2-a]indolediones. Adv. Syn. & Cat. 2024, 366(5), 1158-1164.

3. Yongmei Xiao, Yaowen Liu, Liangru Yang, Yingjun Wang, Jinwei Yuan, Lingbo Qu. Synthesis and crystal structure of a chelating N‑heterocyclic carbene palladium complex containing N‑(3‑bromopropyl)‑N’‑thioether-difunctionalized imidazol‑2‑ylidene. J. Chem. Crystallogr. 2024, 54(3), 197-202.

4. Shifeng Zhu, Liangru Yang, Yingying Zhao. Ethyl 3‑aminobenzo[b]thiophene- 2‑carboxylate derived ratiometric schiff base fluorescent sensor for the recognition of In³⁺ and Pb²⁺. J. Fluoresc. 2024, 1-11.

5. Liangru Yang, Yixin Li, Haifan Zhang, Changming Tian, Qiaohong Cao, Yongmei Xiao, Libo Yuan, Guoxing Liu. Photoisomerization, assembling and fluorescence photoswitching behaviors of a water-soluble stiff-stilbene with cucurbit[7]uril. Chin. Chem. Lett. 2023, 34(8), 108108.

6. Liangru Yang, Mengli Guo, Jinwei Yuan, Jiamei Wang, Yuting Xia, Yongmei Xiao, Pu Mao. Research progress on pincer N-heterocyclic carbene metal complexes. Chin. J. Org. Chem. 2023, 43(6), 2002-2025.

7. Shouren Zhang, Jinwei Yuan, Guangchao Huang, Chengjia Ma, Jingjing Yang, Liangru Yang, Yongmei Xiao, Lingbo Qu. Visible-light-induced intramolecular tandem cyclization of unactivated indoloalkynes for the synthesis of sulfonylated and selenylated indolo[1,2-a]quinolones. J. Org. Chem. 2023, 88(16): 11712-11727

8. Xianghui Meng, Liangru Yang, Qilin Liu, Zhenhua Dong, Jinwei Yuan, Yongmei Xiao, Pu Mao. Amide functionalized pyridine/pyrimidine chelating N-heterocyclic carbene palladium complexes: Synthesis, structure, and catalysis for c-5 arylation of imidazoles. Chin. J. Org. Chem. 2022, 42(11), 3747-3756.

9. Pu Mao, Liangru Yang, Yongmei Xiao, et al. Synthesis of chiral imidazole amino alcohols and their application in the asymmetric copper-catalyzed henry reaction. Chin. J. Org. Chem. 2019, 39(2), 443-448.

10. Jinwei Yuan, Liangru Yang, Pu Mao, et al. AgNO₃-catalyzed direct C–H arylation of quinolones by oxidative decarboxylation of aromatic carboxylic acids, Org. Chem. Front. 2017, 4, 545-554.

11. Liangru Yang, Xinchi Zhang, Jinwei Yuan, et al. Catalytic activity of chelating N-heterocyclic carbene palladium complexes towards selective phosphorylation of coumarins. J. Organomet. Chem. 2016, 818, 179-184.

12. Liangru Yang, Wenjun Zhang, Yongmei Xiao,et al. Picolyl functionalised chelating N-heterocyclic carbene palladium complexes: Synthesis and catalytic activity towards suzuki cross-coupling in water. ChemistrySelect, 2016, 4, 680-684.

13. Jinwei Yuan, Liangru Yang, Yongmei Xiao, et al. Novel synthesis of steryl esteryl esters from -sitosterol and N-phosphoryl amino acid under microwave irradiation. Phosphorus Sulfur and Silicon and the Related Elements, 2016, 191, 1358-1361

14. Jinwei, Yuan, Liangru Yang, Qiuyue Yin, et al. KMnO₄/AcOH-mediated C3-selective direct arylation of coumarins with arylboronic acids. RSC Adv. 2016, 6(42), 35936-35944.

15. Liangru Yang, Jinwei Yuan, Pu Mao, et al. Chelating palladium complexes containing pyridine/pyrimidine hydroxyalkyl di-functionalized N-heterocyclic carbenes: Synthesis, structure, and catalytic activity towards C-H activation. RSC Adv. 2015, 5(130), 107601-107607.

16. Liangru Yang, Qi Guo, Yongmei Xiao, et al. Development of chelating N-heterocyclic carbene metal complexes. Chin. J. Org. Chem. 2015, 35(9), 1834-1837.

17. Liangru Yang, Xinchi Zhang, Pu Mao, et al. NCN Pincer palladium complexes based on 1,3-dipicolyl-3,4,5,6-tetrahydropyrimidin-2-ylidenes: Synthesis, characterization and catalytic activities. RSC Adv. 2015, 5(33), 25723-25729.

18. Liangru Yang, Huanyu Bian, Wenpeng Mai, et al. Synthesis of tetrahydropyrimidinium salts and their in situ catalytic activities towards Buchwald-Hartwig amination reaction under microwave irradiation. Turk. J. Chem. 2015, 39, 121-129.